Intralesional Therapy for Hair Loss

Intralesional therapy is a specialized treatment approach that targets specific areas of the scalp to address various forms of hair loss, such as alopecia areata, patchy hair loss, and inflammatory scalp conditions. By directly delivering medications to the affected area, this method provides concentrated results with minimal systemic side effects.

Intralesional therapy involves injecting medications directly into the scalp to address hair loss or inflammation. It is particularly effective in cases like:

• Alopecia Areata: An autoimmune condition where the immune system attacks hair follicles, causing patchy hair loss.
• Inflammatory Scalp Conditions: Conditions that cause localized hair loss due to inflammation.

1. 1. Intralesional Steroids
   • How it Works: Steroids like triamcinolone are injected into the scalp to suppress inflammation and modulate the immune response.
   • Benefits: Stimulates regrowth in affected areas, reduces redness, swelling, and immune activity around hair follicles.
   • Effectiveness: Best for early-stage alopecia areata or inflammatory hair loss.
2. 2. Intralesional Microneedling with Immunosuppressives (e.g., Tofacitinib)
   • How it Works: Microneedling enhances the delivery of immunosuppressive medications like tofacitinib, which modulates the immune response and reduces follicular damage.
   • Benefits: Promotes hair regrowth by suppressing autoimmune activity while improving scalp blood flow and collagen production.
   • Effectiveness: Suitable for persistent or extensive cases of alopecia areata and other resistant inflammatory hair loss conditions.